EPS15（epidermal growth factor receptor pathway substrate 15），癌症关联基因，基因ID：2060，这个基因编码一种属于egfr途径的蛋白质。该蛋白存在于clatherin包被的凹坑中，参与受体介导的egf内吞作用。值得注意的是，在急性髓性白血病中，该基因与hrx/all/mll基因重排。选择性剪接导致编码不同亚型的多个转录变体。[由RefSeq提供，2009年5月]This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably， this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq， May 2009]。