ELMO1(engulfment and cell motility 1),癌症关联基因,基因ID:9844,这个基因编码吞噬和细胞运动蛋白家族的一个成员这些蛋白与胞质分裂蛋白的特异性分子相互作用,促进吞噬和细胞迁移该基因和胞质分裂因子1的表达增加可能促进胶质瘤细胞的侵袭,其单核苷酸多态性可能与糖尿病肾病有关选择性剪接导致多个转录变体[由RefSeq提供,2013年8月]This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]。