CDH9（cadherin 9），癌症关联基因，基因ID：1007，这个基因编码一种典型的ii型钙黏蛋白，来自钙黏蛋白超家族，是介导钙依赖性细胞粘附的完整膜蛋白。成熟的钙粘蛋白由一个大的N端胞外结构域、一个单一的跨膜结构域和一个小的高度保守的C端胞质结构域组成细胞外结构域由5个亚结构域组成，每个亚结构域都包含一个钙粘蛋白基序，似乎决定了该蛋白的嗜同细胞粘附活性的特异性II型（非典型）钙粘蛋白的定义是基于其缺乏一个特定于I型钙粘蛋白的HAV细胞粘附识别序列。[由RefSeq提供，2008年7月]This gene encodes a type II classical cadherin from the cadherin superfamily， integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain， a single membrane-spanning domain， and a small， highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains， each containing a cadherin motif， and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. [provided by RefSeq， Jul 2008]。