LASP1（LIM and SH3 protein 1），癌症关联基因，基因ID：3927，该基因编码lim蛋白亚家族的一个成员，其特征是lim基序和src同源区3的结构域，同时也是肌动蛋白结合蛋白星云家族的一个成员。编码蛋白是一种camp和cgmp依赖的信号蛋白，在细胞膜的延伸处与肌动蛋白细胞骨架结合。编码的蛋白质与转移性乳腺癌、血液肿瘤如b细胞淋巴瘤和结直肠癌有关。[由RefSeq提供，2012年10月]This gene encodes a member of a subfamily of LIM proteins， characterized by a LIM motif and a domain of Src homology region 3， and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer， hematopoetic tumors such as B-cell lymphomas， and colorectal cancer. [provided by RefSeq， Oct 2012]。