RPTOR（regulatory associated protein of MTOR complex 1），癌症关联基因，基因ID：57521，该基因编码一个信号通路的组成部分，该信号通路调节细胞生长以响应营养素和胰岛素水平。编码蛋白与mtor激酶形成化学计量复合物，并与真核起始因子4e结合蛋白-1和核糖体蛋白s6激酶相关。该蛋白正调控下游效应核糖体蛋白s6激酶，负调控mtor激酶。已发现该基因编码不同亚型的多个转录变体。[由RefSeq提供，2009年9月]This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase， and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase， and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq， Sep 2009]。