RIT1（Ras like without CAAX 1），癌症关联基因，基因ID：6016，该基因编码ras相关GTPase亚家族的一个成员。编码蛋白参与调节与细胞应激相关的p38 mapk依赖性信号级联。该蛋白还与神经生长因子协同促进神经元的发育和再生。交替剪接导致多个转录变体。This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.关联癌症：子宫内膜癌，肺腺癌。关联化疗药物：Pictilisib，司美替尼。