APOBEC3B(apolipoprotein B mRNA editing enzyme catalytic subunit 3B),癌症关联基因,基因ID:9582,该基因属于胞苷脱氨酶基因家族。它是在22号染色体上发现的7个相关基因或假基因之一,被认为是基因复制的结果。该簇的成员编码的蛋白质在结构和功能上与编辑cytidine脱氨酶APOBEC1的C到U RNA相关人们认为这些蛋白质可能是RNA编辑酶,在生长或细胞周期控制中起作用一个杂合基因是由该基因ApBEC3B和相邻基因ApBEC3A缺失约29.5 kb的序列导致的,缺失位点位于两个基因内,因此缺失等位基因被预测为APOBEC3A的启动子和编码区。但是apobec3b的3’utr。已经发现了两个编码不同亚型的转录变体。[由RefSeq提供,2012年7月]This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoin。