ZNF384（zinc finger protein 384），癌症关联基因，基因ID：171017，该基因编码一种C2H2型锌指蛋白，可能作为转录因子发挥作用该基因还含有编码连续谷氨酰胺残基的长CAG三核苷酸重复序列该蛋白似乎结合并调节细胞外基质基因MMP1、MMP3、MMP7和COL1A1的启动子小鼠的研究表明，核基质转录因子（NP/NMP4）可能是细胞外基质重塑过程中连接细胞结构和功能的一般机械途径的一部分选择性剪接导致多个转录变体在急性白血病中观察到该基因与22号染色体上的EWSR1、17号染色体上的TAF15基因或19号染色体上的TCF3（E2A）基因反复重排在7号染色体上发现了一个相关的假基因。[由RefSeq提供，2011年4月]This gene encodes a C2H2-type zinc finger protein， which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1， MMP3， MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with。