SGCZ（sarcoglycan zeta），癌症关联基因，基因ID：137868，zeta肉瘤聚糖基因的大小超过465kb，定位于8p22。这种蛋白质是肉聚糖复合物的一部分，由6种蛋白质组成肉瘤聚糖均为N-糖基化跨膜蛋白，具有短的细胞内结构域、单一的跨膜结构域和大的胞外结构域，其中含有羧基末端簇和一些保守的半胱氨酸残基肌甘聚糖复合物是肌营养不良相关糖蛋白复合物（dgc）的一部分，它连接细胞内骨架和细胞外基质。[由RefSeq提供，2008年7月]The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex， a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain， a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC)， which bridges the inner cytoskeleton and the extra-cellular matrix. [provided by RefSeq， Jul 2008]。