PRIM2（DNA primase subunit 2），癌症关联基因，基因ID：5558，这个基因编码的是DNA原酶的58k亚单位，这是一种在DNA复制中起关键作用的酶编码的蛋白质形成一个具有49k道尔顿亚单位的异二聚体这种异二聚体作为一种DNA导向的RNA聚合酶，合成小RNA引物，用于在DNA的滞后链上产生冈崎片段该基因的选择性剪接导致多个转录变体。这个基因有一个相关的假基因，也存在于6号染色体上。[由RefSeq提供，2014年4月]This gene encodes the 58 kilodalton subunit of DNA primase， an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. Alternative splicing of this gene results in multiple transcript variants. This gene has a related pseudogene， which is also present on chromosome 6. [provided by RefSeq， Apr 2014]。