PIBF1（progesterone immunomodulatory binding factor 1），癌症关联基因，基因ID：10464，这个基因编码一种由类固醇激素孕酮诱导的蛋白质，在维持妊娠中起作用。编码蛋白调节免疫系统的多个方面，以促进正常妊娠，包括细胞因子合成，自然杀伤（nk）细胞活性和花生四烯酸代谢。血清中这种蛋白的低水平与人类自然分娩有关这种蛋白可能促进胶质瘤的增殖、迁移和侵袭[由RefSeq提供，2017年3月]This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis， natural killer (NK) cell activity， and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation， migration and invasion of glioma. [provided by RefSeq， Mar 2017]。