RAD54L（RAD54 like），癌症关联基因，基因ID：8438，该基因编码的蛋白质属于类死亡螺旋酶超家族，与酿酒酵母rad54相似，后者参与dna的同源重组和修复。该蛋白在dna双链断裂的同源重组修复中起着重要作用。这种蛋白质与双链dna的结合引起dna拓扑结构的改变，这被认为有助于同源dna的切割，并刺激dna重组。选择性剪接导致编码相同蛋白质的多个转录变体。[由RefSeq提供，2008年12月]The protein encoded by this gene belongs to the DEAD-like helicase superfamily， and shares similarity with Saccharomyces cerevisiae Rad54， a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change， which is thought to facilitate homologous DNA paring， and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq， Dec 2008]。