KEL(Kell metallo-endopeptidase (Kell blood group)),癌症关联基因,基因ID:3792,该基因编码一种II型跨膜糖蛋白,是高度多态性的Kell血型抗原。kell糖蛋白通过一个二硫键连接到携带kx抗原的xk膜蛋白。编码的蛋白质包含锌内肽酶的尼泊尔素(m13)家族成员的序列和结构相似性。[由RefSeq提供,2008年7月]This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]。