PDCD4（programmed cell death 4 (neoplastic transformation inhibitor)），癌症关联基因，基因ID：27250，该基因是一种肿瘤抑制因子，编码一种与真核细胞翻译起始因子4A1结合并通过阻止RNA结合抑制其功能的蛋白质。选择性剪接导致多个转录变体。This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.关联癌症：肺癌。