KMT2C（lysine methyltransferase 2C），癌症关联基因，基因ID：58508，该基因是髓系/淋巴系或混合系白血病（MLL）家族的成员，编码核蛋白，具有AT-Hook DNA结合域、DHHC型锌指、六个PhD型锌指、一个集合域、一个后集合域和一个环状锌指。该蛋白是ASC-2/NCOA6复合物（ASCOM）的成员，具有组蛋白甲基化活性，参与转录协同激活。This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain， a DHHC-type zinc finger， six PHD-type zinc fingers， a SET domain， a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM)， which possesses histone methylation activity and is involved in transcriptional coactivation.关联癌症：乳腺癌。关联化疗药物：依西美坦，来曲唑片。