DNM2（dynamin 2），癌症关联基因，基因ID：1785，动态蛋白是gtp结合蛋白的一个亚家族。这些蛋白质在含有gtpase结构域的分子的n端部分具有相当大的序列相似性。动力与微管有关它们与细胞内吞和细胞运动等细胞过程，以及伴随某些活动（如破骨细胞的骨吸收）的膜改变有关。动力蛋白结合许多结合肌动蛋白和其他细胞骨架蛋白的蛋白质动力也可以自我组装，一个刺激GTPase活性的过程已经描述了五种编码不同蛋白质的选择性剪接转录本。额外的交替剪接转录物可能存在，但它们的全长性质尚未确定。[由RefSeq提供，2010年6月]Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule， which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility， and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble， a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional。