TCF12（transcription factor 12），癌症关联基因，基因ID：6938，该基因编码的蛋白质是碱性螺旋环螺旋（bhlh）e蛋白家族的一员，该家族识别一致结合位点（e-box）canntg。这种编码蛋白在许多组织中表达，其中包括骨骼肌、胸腺、B细胞和T细胞，并可能通过与其他bHLH E蛋白形成异二聚体参与调节谱系特异性基因表达已经描述了该基因的几个选择性剪接的转录变体，但其中一些变体的全长性质尚未确定。[由RefSeq提供，2008年7月]The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues， among them skeletal muscle， thymus， B- and T-cells， and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described， but the full-length nature of some of these variants has not been determined. [provided by RefSeq， Jul 2008]。