GATA2(GATA binding protein 2),癌症关联基因,基因ID:2624,该基因编码一个锌指转录因子GATA家族的成员,该家族以它们在靶基因启动子区域结合的一致核苷酸序列命名。编码蛋白在调节参与造血和内分泌细胞谱系发育和增殖的基因转录中起着重要作用。选择性剪接导致多个转录变体。This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.关联癌症:肺腺癌。关联化疗药物:硼替佐米。