SPRED1(sprouty related EVH1 domain containing 1),癌症关联基因,基因ID:161742,这个基因编码的蛋白质是芽苗菜蛋白家族的一员,在多种生长因子的作用下被酪氨酸激酶磷酸化编码的蛋白质可以作为一个同二聚体或一个异二聚体与SPRED2调节激活的MAP激酶级联该基因缺陷是1型神经纤维瘤病样综合征(nfls)的病因之一。[由RefSeq提供,2008年7月]The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]。