CD70（CD70 molecule），癌症关联基因，基因ID：970，该基因编码的蛋白是一种细胞因子，属于肿瘤坏死因子（TNF）配体家族。这种细胞因子是TNFRSF27/CD27的配体。它是活化的T淋巴细胞和B淋巴细胞的表面抗原，而不是静止的T淋巴细胞和B淋巴细胞的表面抗原。它诱导共刺激t细胞的增殖，促进溶细胞t细胞的产生，并有助于t细胞的活化。该细胞因子还被报道在调节B细胞活化、自然杀伤细胞的细胞毒性功能和免疫球蛋白合成中发挥作用。[由RefSeq提供，2008年7月]The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated， but not on resting， T and B lymphocytes. It induces proliferation of costimulated T cells， enhances the generation of cytolytic T cells， and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation， cytotoxic function of natural killer cells， and immunoglobulin sythesis. [provided by RefSeq， Jul 2008]。