CHUK(component of inhibitor of nuclear factor kappa B kinase complex),癌症关联基因,基因ID:1147,这个基因编码丝氨酸/苏氨酸蛋白激酶家族的一个成员。编码蛋白是一种细胞因子激活蛋白复合物的组成部分,它是必需转录因子nf-kappa-b复合物的抑制剂,磷酸化位点通过增溶途径触发抑制剂的降解,从而激活转录因子。[由RefSeq提供,2008年7月]This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]。